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The majority of current subcellular screening technologies rely on fluorescent labeling of targets. Because Visible™ functions equally well with any light source, all current reagents and protocols can be utilized by it seamlessly. A major distinction, however, is that unlike other available products, Visible™ is capable of following dynamic intracellular phenomena in real time leading to a more accurate depiction and better resulting data. Reify has validated Visible™ in a number of different systems including nuclear translocation, calcium ion flux and chromosome dynamics.